2008 INIAstress Publications

Abdeltawab NF, Aziz RK, Kansal R, Rowe SL, Su Y, Gardner L, Brannen C, Nooh MM, Attia RR, Abdelsamed HA, Taylor WL, Lu L, Williams RW, Kotb M. An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis. PLoS Pathog. 2008 Apr 18;4(4):e1000042. doi: 10.1371/journal.ppat.1000042. PubMed PMID: 18421376; PubMed Central PMCID: PMC2277464.

Becker HC (2008) Alcohol Dependence, Withdrawal, and Relapse. Alcohol Research & Health 31:348-361.

Becker HC, Lopez MF, Morrow AL. Neurosteroid Allopregnanolone involvement in Ethanol dependence and drinking behavior in C57BL/6J mice. Alcohol, 42 (4) 2008.

Bennett B, Carosone-Link PJ, Beeson M, Gordon L, Phares-Zook N, Johnson TE. Genetic dissection of QTLs for ethanol sensitivity in Long- and Short-Sleep mice. Genes Brain Behav, 2008 Aug;7(6):659-68. PMID: 18363857.

Brigman JL, Mathur P, Lu L, Williams RW and Holmes A: Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice. Behavioural Pharmacology 2008 Sep 30. PMID: 18830130 , PMCID: PMC2701299.

Chen X, Wang L, Smith JD, Zhang B. Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes. Bioinformatics. 2008 Nov 1;24(21):2474-81. doi: 10.1093/bioinformatics/btn458. Epub 2008 Aug 27. PubMed PMID: 18753155; PubMed Central PMCID: PMC2732277.

Chesler EJ, Miller DR, Branstetter LR, Galloway LD, Jackson BL, Philip VM, Voy BH, Culiat CT, Threadgill DW, Williams RW, Churchill GA, Johnson DK, Manly KF. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome. 2008 Jun;19(6):382-9. PMID: 18716833, PMCID: PMC2745091.

Ding M, Lu L, Toth LA. Gene expression in lung and basal forebrain during influenza infection in mice.Genes Brain Behav. 2008 Mar;7(2):173-83. Epub 2007 Aug 13. PMID: 17696998.

Druka A, Druka I, Centeno AG, Li H, Sun Z, Thomas WT, Bonar N, Steffenson BJ, Ullrich SE, Kleinhofs A, Wise RP, Close TJ, Potokina E, Luo Z, Wagner C, Schweizer GF, Marshall DF, Kearsey MJ, Williams RW, Waugh R. Towards systems genetic analyses in barley: Integration of phenotypic, expression and genotype data into GeneNetwork. BMC Genet. 2008 Nov 18;9:73. doi: 10.1186/1471-2156-9-73. PubMed PMID: 19017390; PubMed Central PMCID: PMC2630324.

Eblen, J. D., Gerling, I. C., LANGSTON, M. A., Saxton, A. M. and SNODDY, J. R. Graph Algorithms for Integrated Biological Analysis, with Applications to Type 1 Diabetes Data, in Clustering Challenges in Biological Networks (S. Butenko, W. A. Chaovalitwongse and P. Pardalos, editors), World Scientific, 2008.

Espana R and Jones SR (2008) A Neurochemical Perspective on Dopamine in The Nucleus Accumbens, in: The Nucleus Accumbens: Neurotransmitters and Related Behaviours, Helene David, Ed., Research Signpost, Kerala, India.

Gardner D, Akil H, Ascoli GA, Bowden DM, Bug W, Donohue DE, Goldberg DH, Grafstein B, Grethe JS, Gupta A, Halavi M, Kennedy DN, Marenco L, Martone ME, Miller PL, MÃller HM, Robert A, Shepherd GM, Sternberg PW, Van Essen DC, Williams RW. The neuroscience information framework: a data and knowledge environment for neuroscience. Neuroinformatics. 2008 Sep;6(3):149-60. PMID: 18946742, PMCID: PMC2661130.

Grant KA, Leng X, Green HL, Szeliga KT, Rogers LS, Gonzales SW. Drinking typography established by scheduled induction predicts chronic heavy drinking in a monkey model of ethanol self-administration. Alcohol Clin Exp Res. 2008 Oct;32(10):1824-38. doi: 10.1111/j.1530-0277.2008.00765.x. Epub 2008 Aug 12. PubMed PMID: 18702645; PubMed Central PMCID: PMC2847427.

Grant KA, Helms CM, Rogers LS, Purdy RH. Neuroactive steroid stereospecificity of ethanol-like discriminative stimulus effects in monkeys. J Pharmacol Exp Ther. 2008 Apr 24. PMID: 18436788, PMCID: PMC2562878.

Grant KA, Stafford, J, Thiede A, Kiley C, Odagiri M, Ferguson B. Who’s at risk? Population characterization of alcohol self-administration in nonhuman primates helps identify pathways to dependence. Alcohol Research and Health. 2008 31 (4).

Griffin III WC, Yanke AB, Frederick-Duus D, Randall JS, Fadel J, Becker HC. Influence of Chronic Ethanol Exposure and Withdrawal on Cholinergic Neurotransmission in the Nucleus Accumbens of Mice. Alcoholism: Clinical and Experimental Research, 32 (6), page 156A, 2008.

Grisel JE, Bartels JL, Allen SA, Turgeon VL. Influence of beta-Endorphin on anxious behavior in mice: interaction with EtOH. Psychopharmacology (Berl). 2008 Sep;200(1):105-15. PMID: 18604523, PMCID: PMC2818628.

Grueter BA, McElligott ZA, Robison AJ, Mathews GC, Winder DG. In vivo metabotropic glutamate receptor 5(mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression. J Neurosci. 2008 Sep 10;28(37):9261-70. doi: 10.1523/JNEUROSCI.2886-08.2008. PubMed PMID: 18784306; PubMed Central PMCID: PMC2562219.

Guo AY, Webb BT, Miles MF, Zimmerman MP, Kendler KS, Zhao Z. ERGR: An ethanol-related gene resource. Nucleic Acids Res. 2009 Jan;37(Database issue):D840-5. doi: 10.1093/nar/gkn816. Epub 2008 Oct 31. PubMed PMID: 18978021; PubMed Central PMCID: PMC2686553.

Griffin WC 3rd, Lopez MF, Yanke AB, Middaugh LD, Becker HC. Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens. Psychopharmacology (Berl). 2009 Jan;201(4):569-80. PMID: 18791704, PMCID: PMC2590623.

Healey JC, Winder DG, Kash TL. Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions. Alcohol. 2008 May;42(3):179-90. doi: 10.1016/j.alcohol.2008.01.003. Epub 2008 Mar 20. PubMed PMID: 18358675; PubMed Central PMCID: PMC2855295.

Helms CM, Rogers LS, Grant KA. Gamma-hydroxybutyric acid in male and female cynomolgus monkeys trained to discriminate 1.0 or 2.0 g/kg ethanol. Behav Pharmacol. 2008 Jul;19(4):317-324. PMID: 18622179, PMCID: PMC2704122.

Helms CM, Rogers LS, Waters CA, Grant KA. Zolpidem Generalization and Antagonism in Male and Female Cynomolgus Monkeys Trained to Discriminate 1.0 or 2.0 g / kg Ethanol. Alcohol Clin Exp Res. 2008 May 14. PMID: 18482161, PMCID: PMC2517055.

Hitzemann R, Oberbeck D. Conclusions. Alcohol Res Health. 2008;31(3):278. PubMed PMID: 25275167; PubMed Central PMCID: PMC3860485.

Jan TA, Lu L, Li CX, Williams RW, Waters RS (2008) Genetic analysis of posterior medial barrel subfield (PMBSF) size in somatosensory cortex (SI) in recombinant inbred strains of mice. BMC Neuroscience 9:3. PMID: 18179704, PMCID: PMC2254631.

Kash TL, Matthews RT, Winder DG. Alcohol inhibits NR2B-containing NMDA receptors in the ventral bed nucleus of the stria terminalis. Neuropsychopharmacology. 2008 May;33(6):1379-90. Epub 2007 Jul 11. PubMed PMID:17625498; PubMed Central PMCID: PMC2864636.

Kash TL, Nobis WP, Matthews RT, Winder DG. Dopamine enhances fast excitatory synaptic transmission in the extended amygdala by a CRF-R1-dependent process. J Neurosci. 2008 Dec 17;28(51):13856-65. PMID: 19091975, PMCID: PMC2630395.

Kerns RT, Miles MF. Microarray analysis of ethanol-induced changes in gene expression. Methods Mol Biol. 2008;447:395-410. doi: 10.1007/978-1-59745-242-7_26. Review. PubMed PMID: 18369932.

Lack, A.K., Ariwodola, O.J., Chappell, A.M., Weiner, J.L., and McCool, B.A. (2008) Ethanol inhibition of kainite receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala.Neuropharm. 55: 661-668. PMID: 18617194, PMCID: PMC2615485.

Langston MA, Perkins AD, Saxton AM, Scharff JA and Voy BH, Innovative Computational Methods for Transcriptomic Data Analysis: A Case Study in the Use of FPT for Practical Algorithm Design and Implementation, The Computer Journal 51 (2008), 26-38.

Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC. Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC Genomics. 2008 Sep 25;9:444. PMID: 18817551, PMCID: PMC2570693.

Matthews DB, Chesler EJ, Cook MN, Cockroft J, Philip VM, Goldowitz D. Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains. Behav Genet. 2008 Jul;38(4):417-23. doi: 10.1007/s10519-008-9210-7. Epub 2008 Jun 6. PubMed PMID: 18535899; PubMed Central PMCID: PMC2504763.

Matthews DB, Morrow AL, O'Buckley T, Flanigan TJ, Berry RB, Cook MN, Mittleman G, Goldowitz D, Tokunaga S, Silvers JM.Acute mild footshock alters ethanol drinking and plasma corticosterone levels in C57BL/6J male mice, but not DBA/2J or A/J male mice.Alcohol. 2008 Jul 1. PMID: 18599253. PMCID: PMC2575102.

Matthews DB, Tinsley KL, Diaz-Granados JL, Tokunaga S, Silvers JM. Chronic intermittent exposure to ethanol during adolescence produces tolerance to the hypnotic effects of ethanol in male rats: a dose-dependent analysis. Alcohol. 2008 Dec;42(8):617-21. PMID: 19038695.

McElligott ZA, Winder DG. Alpha1-adrenergic receptor-induced heterosynaptic long-term depression in the bed nucleus of the stria terminalis is disrupted in mouse models of affective disorders. Neuropsychopharmacology. 2008 Sep;33(10):2313-23. Epub 2007 Nov 28. PubMed PMID: 18046308; PubMed Central PMCID: PMC3046390.

McLachlan SM, Aliesky HA, Pichurin PN, Chen CR, Williams RW, Rapoport B. Shared and unique susceptibility genes in a mouse model of Graves' disease determined in BXH and CXB recombinant inbred mice. Endocrinology. 2008 Apr;149(4):2001-9. Epub 2007 Dec 27. PubMed PMID: 18162518; PubMed Central PMCID: PMC2276708.

Mozhui K, Ciobanu DC, Schikorski T, Wang X, Lu L, Williams RW (2008) Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genetics 4:e1000260. PMID: 19008955, PMCID: PMC2577893.

Mulligan MK, Ponomarev I, Boehm SL 2nd, Owen JA, Levin PS, Berman AE, Blednov YA, Crabbe JC, Williams R, Miles M, Bergeson SE."Alcohol Trait and Transcriptional Genomic Analysis of C57BL/6 Substrains"Genes Brain Behav. 2008 May 26. PMID: 18397380.

New J, Kendall W, Huang J, Chesler E.Dynamic visualization of coexpression in systems genetics data.IEEE Trans Vis Comput Graph. 2008 Sep-Oct;14(5):1081-95.PMID: 18599919.

Olsen CM, Huang Y, Goodwin S, Ciobanu DC, Lu L, Sutter TR, Winder DG. Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum. Physiol Genomics. 2008 Feb 19;32(3):283-98. PMID: 17911379.

Peirce JL, Browman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW (2008) Genome reshuffling for advanced intercross permutation (GRAIP): A permutation method for quantitative advanced intercross population analysis. PLoS One 3:e1977. PMID: 18431467, PMCID: PMC2295257.

Porcu P, O'Buckley TK, Leslie Morrow A, Adinoff B. Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects. Psychoneuroendocrinology. 2008 Feb;33(2):214-26. PMID: 18096321, PMCID: PMC2262103.

Reiner DJ, Jan TA, Boughter JD Jr, Li CX, Lu L, Williams RW, Waters RS.Genetic Analysis of Tongue Size and Taste Papillae Number and Size in Recombinant Inbred Strains of Mice.Chem Senses. 2008 Jul 24. PMID: 18653645, PMCID: PMC2565774.

Rosen GD, Pung CJ, Owens CB, Caplow J, Kim H, Mozhui K, Lu L, Williams RW. Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice. Genes Brain Behav. 2008 Jan 9. PMID: 19191878, PMCID: PMC2706028.

Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S. Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Neuropsychopharmacology. 2008 Nov;33(12):2981-92. doi: 10.1038/npp.2008.15. Epub 2008 Feb 20. PubMed PMID: 18288092; PubMed Central PMCID: PMC2746694.

Vázquez-Chona FR, Lu L, Williams RW, Geisert EE. Genomic loci modulating the retinal transcriptome in wound healing. Gene Regul Syst Bio. 2008 Feb 14;1:327-48. PubMed PMID: 19936100; PubMed Central PMCID: PMC2759132.

Williams RW, Lu L (2008) Integrative genetic analysis of alcohol dependence using the GeneNetwork web resources. In Pathways to Alcohol Dependence: Alcohol Research & Health 31:275-277.

Yang RJ, Mozhui K, Karlsson RM, Cameron HA, Williams RW, Holmes A. Variation in Mouse Basolateral Amygdala Volume is Associated With Differences in Stress Reactivity and Fear Learning. Neuropsychopharmacology. 2008 Jan 9. PMID: 18185497.